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In a very recent analyze, we reported the identification plus the characterization of a fresh atypical opioid receptor with exclusive detrimental regulatory Houses in the direction of opioid peptides.1 Our success showed that ACKR3/CXCR7, hitherto called an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is additionally a wide-spectru